This communication reflects the views of the APPROACH consortium and neither IMI nor the European Union and EFPIA are liable for any use that may be made of the information contained herein.

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The research leading to these results has received support from the Innovative Medicines Initiative Joint Undertaking under grant Agreement n° 115770, resources of which are composed of financial contribution from the European Union's Seventh Framework Programme (FP7/2007-2013) and EFPIA companies’ in kind contribution.