Work package 1: Bioinformatics
WP1 focuses on the development of an integrated bioinformatics platform that functions as a repository of clinical data, biomarker data, images, as well as storage of bio-tissues from a broad spectrum of OA patients.
Work package 2: Biochemical marker discovery, validation and testing
WP2 focuses on, proteomics, metabolomics and lipidomics analyses to identify novel and current (validated) markers for validation and qualification.
Work package 3: Cohort & imaging
WP3 covers different OA aetiologies (phenotypes) in numbers that fulfil basic requirements for further statistical and bioinformatics studies, which will be performed in WP1.
Work package 4: Management
WP4 is the consortium management layer, which will ensure optimal collaboration between partners and relevant stakeholders, and knowledge exchange between the WPs.
The research leading to these results has received support from the Innovative Medicines Initiative Joint Undertaking under grant Agreement n° 115770, resources of which are composed of financial contribution from the European Union's Seventh Framework Programme (FP7/2007-2013) and EFPIA companies’ in kind contribution. See IMI Europe.
