Work package 3: Cohort & Imaging

Work package 3: APPROACH cohort and Biomarker Validation and Qualification

In WP 3 the defined subtypes in WP 1 will be included in the longitudinal APPROACH cohort. WP3 covers different OA aetiologies (phenotypes) in numbers that fulfil basic requirements for further statistical and bioinformatics studies, which will be performed in WP1. 

The biomarkers to be measured in the longitudinal APPROACH cohort will help to further stratify to aetiological phenotypes, which will clearly differentiate patients based on biomarker profiles and place them in an OA severity and progression scale.

Work package leads:

Floris Lafeber

Utrecht University Medical Center, The Netherlands

Agnès Lalande

Servier, France